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Albumin: The Multifunctional Protein at the Heart of Human Physiology
Albumin, the most abundant protein in human blood plasma, has emerged as a critical focus of medical research due to its diverse physiological roles and therapeutic applications. Synthesized exclusively by the liver at a rate of approximately 10-15 grams per day, this 66-kilodalton protein constitutes about 50-60% of total plasma protein content and plays indispensable roles in maintaining human health.
Structural and Functional Significance
The albumin molecule consists of a single polypeptide chain containing 585 amino acids arranged in a heart-shaped tertiary structure. This unique configuration enables albumin to perform multiple essential functions simultaneously. Its primary role involves maintaining colloid osmotic pressure, which prevents fluid from leaking out of blood vessels into tissues. Without adequate albumin levels, patients experience edema and ascites, conditions characterized by abnormal fluid accumulation.











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